Journal of Environmental Biology

A preliminary study on the anti-inflammatory activity of

methanol extract of Ulva lactuca in rat

 

R. Jothibai Margret*¹,^? S. Kumaresan² and S. Ravikumar³

¹Department of Chemistry, Pope?s College, Sawyerpuram - 628 251, India

²Department of Chemistry, Manonmaniam Sundaranar University, Tirunelveli - 627 012,? India

³Department of Oceanography and Coastal Area Studies, Division of Marine Microbiology and

Infectious Medicine, Alagappa University, Thondi campus, Thondi - 623 409, India

(Received: June 15, 2007; Revised received: October 20, 2007; Re-revised received: February 25, 2008; Accepted: July 28, 2008)

 

Abstract: Anti-inflammatory drugs presently available for the treatment of various inflammatory disorders have diverse and undesirable side effects. In recent years; active principles of varied chemical structures have been isolated from plants possessing anti-inflammatory activity. Sulfated polysaccharides present in algae were shown to posses anti-inflammatory properties. Ulva lactuca the green alga available in Tuticorin coast was found to show anti-inflammatory effect as evidenced by the reduction in the inhibition of oedema at the 4^th day of the experiment compared with the positive control drug and control.? Microscopic examination of the elite organs did not show any alteration compared with the control and reference group.? Moreover, the hematological parameters were found normal compared with the control. The present study suggests the need for further studies for the development of anti-inflammatory drug of marine origin with proper clinical trials.

Key words: Anti-Inflammatory, Ulva Lactuca, Tuticorin Coast, Drug

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