Google Search the Journal web-site:
|
Abstract - Issue Sep 2024, 45 (5) Back
nstantaneous and historical temperature effects on a-pinene
Biofilm
mediated antibiotic resistant oral bacteria among Parkinson's patients
YJ. Joel1,
P. Xavier2, J.S. Pillai3, T.S. Sujitha1, A.
Iyer1, S. Sree1 and S. Murugan1*
1Department
of Biotechnology, Karunya Institute of Technology and Sciences, Coimbatore
-641 114, India
2Department
of Mathematics, Karunya Institute of Technology and Sciences, Coimbatore -641
114, India
3Department
of Medical Laboratory Science, Komar University of Science and Technology,
Sulaimaniyah, Kurddistan, 46001, Iraq
Received: 16 April
2024 Revised: 26 May 2024 Accepted:
10 July 2024
*Corresponding Author Email : micromurugans@gmail.com
*ORCiD:
https://orcid.org/0000-0002-2432-1883
|
|
|
Abstract
Aim:
The
aim of this study was to examine the oral microbe biofilm and antibiotic
resistance in individuals with Parkinson's disease compared to those without
the condition.
Methodology:
In
this study, the oral bacteria of older patients with Parkinson's disease and
those without the condition were examined for antibiotic resistance and
biofilm formation. In this study, the microbiologists examined oral samples
collected from 33 individual, out of which 18 sufferred from Parkinson's
disease while the remaining 15 individuals were normal. This case involved
the use of the Matrix-Assisted Laser Desorption/Ionization-Time of Flight
(MALDI-TOF) technology to identify six different species.
Results:
The
analysis of oral samples showed the presence of six isolates viz. Staphylococcus
epidermis, S. auricularis, S. simiae, Panebacillus thiaminolyticus, P.
aeruginosa and Bacillus cereus. Out of these, P.
thiaminolyticus was absent in the control group. The incidence of oral
microorganisms was somewhat higher in Parkinson's disease patients than
control individuals, however, there was no discernible variation in the oral
bacterial strains found in the two research groups. The isolates underwent
further analysis following Congo Red Agar and Tissue Culture Plate methods
and showed positive result for biofilm formation. Each isolate found in the
Parkinson's disease groups were found resistant to at least five antibiotics
used.
Interpretation:
The
ability to produce biofilm was present in approximately 83.3% of the isolates
from the Parkinson's disease group and 80% of those from the control group.
This study provides a deeper understanding of the relationship between
biofilm-producing, antibiotic-resistant oral bacteria and Parkinson's
disease, and also address the need for effective management of oral hygiene
in Parkinson’s patients.
Key
words: Antibiotic
resistance, Biofilm, Oral microbiota, Oral health, Parkinson’s disease
|
|
Copyright © 2024 Triveni Enterprises. All rights reserved. No part of the Journal can be
reproduced in any form without prior permission. Responsibility
regarding the authenticity of the data, and the acceptability of the
conclusions enforced or derived, rest completely with the author(s).
|
|
|
|
|
|