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Journal of Environmental Biology

pISSN: 0254-8704 ; eISSN: 2394-0379 ; CODEN: JEBIDP

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    Abstract - Issue Sep 2024, 45 (5)                                     Back


nstantaneous and historical temperature effects on a-pinene

Biofilm mediated antibiotic resistant oral bacteria among Parkinson's patients

 

YJ. Joel1, P. Xavier2, J.S. Pillai3, T.S. Sujitha1, A. Iyer1, S. Sree1 and S. Murugan1*     

1Department of Biotechnology, Karunya Institute of Technology and Sciences, Coimbatore -641 114, India

2Department of Mathematics, Karunya Institute of Technology and Sciences, Coimbatore -641 114, India

3Department of Medical Laboratory Science, Komar University of Science and Technology, Sulaimaniyah, Kurddistan, 46001, Iraq

 

Received: 16 April 2024                   Revised: 26 May 2024                   Accepted: 10 July 2024

*Corresponding Author Email : micromurugans@gmail.com                 *ORCiD: https://orcid.org/0000-0002-2432-1883

 

 

 

Abstract

 

Aim: The aim of this study was to examine the oral microbe biofilm and antibiotic resistance in individuals with Parkinson's disease compared to those without the condition.

Methodology: In this study, the oral bacteria of older patients with Parkinson's disease and those without the condition were examined for antibiotic resistance and biofilm formation. In this study, the microbiologists examined oral samples collected from 33 individual, out of which 18 sufferred from Parkinson's disease while the remaining 15 individuals were normal. This case involved the use of the Matrix-Assisted Laser Desorption/Ionization-Time of Flight (MALDI-TOF) technology to identify six different species.

Results: The analysis of oral samples showed the presence of six isolates viz. Staphylococcus epidermis, S. auricularis, S. simiae, Panebacillus thiaminolyticus, P. aeruginosa and Bacillus cereus. Out of these, P. thiaminolyticus was absent in the control group. The incidence of oral microorganisms was somewhat higher in Parkinson's disease patients than control individuals, however, there was no discernible variation in the oral bacterial strains found in the two research groups. The isolates underwent further analysis following Congo Red Agar and Tissue Culture Plate methods and showed positive result for biofilm formation. Each isolate found in the Parkinson's disease groups were found resistant to at least five antibiotics used.

Interpretation: The ability to produce biofilm was present in approximately 83.3% of the isolates from the Parkinson's disease group and 80% of those from the control group. This study provides a deeper understanding of the relationship between biofilm-producing, antibiotic-resistant oral bacteria and Parkinson's disease, and also address the need for effective management of oral hygiene in Parkinson’s patients.

Key words: Antibiotic resistance, Biofilm, Oral microbiota, Oral health, Parkinson’s disease

 

 

 

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