JEB logo

Journal of Environmental Biology

pISSN: 0254-8704 ; eISSN: 2394-0379 ; CODEN: JEBIDP

About Journal
    Home
    Obituary: Dr. R. C. Dalela
    Editorial Board
    Reviewer Panel
    Publication Policies
    Guidelines for Editors
    Guidelines for Reviewers
    Abstracting and Indexing
    Subscription and Payments
    Contact Journal
    About Triveni Enterprises
 
Read Journal
    Current Issue
    Journal Archives
 
For Authors
    Guidelines for Authors
    Terms and Conditions
    Fees and Payments
    Track Paper Status
 

Google Search the Journal web-site:


    Abstract - Issue Sep 2023, 44 (5)                                     Back


nstantaneous and historical temperature effects on a-pinene

Metabolomic screening for therapeutic potential in Mimela sp., an edible insect of the Arunachal Pradesh region

 

S. Tukshipa, N. Muni, Prveen and J. Chakravorty*

Department of Zoology, Rajiv Gandhi University, Itanagar-791 112, India

 

*Corresponding Author Email : jharna.chakraborty@rgu.ac.in                    *ORCiD: https://orcid.org/0000-0003-3705-8970

 

Received: 03.02.2023                                                                                       Revised: 20.04.2023                                                                    Accepted: 07.06.2023

 

 

Abstract

Aim: Mimela sp. a small coleopteran beetle is rich in proteins, essential amino acids, fatty acids, some vitamins and minerals. It contains nutritional and therapeutic values. Therefore, this study was conducted to identify the bioactive compounds of aqueous and ethanol extracts of Mimela sp. to understand its pharmacological/therapeutic importance.

Methodology: The biologically active metabolites were analysed using Agilent Quadrupole time of flight mass analyser (Q-TOF-MS). Chromatographic separations were performed using 5 ul of aqueous and ethanolic sample injected onto an Agilent ultra high performance liquid chromatography system. Elution was carried out using solvent A (0.1% Formic acid in water) and solvent B (90% Acetonitrile +10% H2O+ 0.1% Formic acid) at a flow rate of 300 ul min-1 for 30 min.

Results: Analysis of both aqueous and ethanol extracts of Mimela sp. showed the presence of important chemical compounds like alpha amino acids (L-Ornithine, (R)-(+)-2-Pyrrolidone-5-Carboxylic acid), monoesters (Ethyl hydrogen sulphate, Carboxylic acid (Benzoic acid), monoterpenoids (Linaylphenylacetate), Cyclic polyols (D-Pinitol), phenols (Vanillic acid, Phyllohydroquinone) and polyphenols (Gentisic acid), which have immunological, antibacterial, antioxidant, anti-inflammatory, anticancer and antiviral properties.

Interpretation: Mimela sp. contain appreciable number. of bioactive compounds which can be further isolated and developed as drugs for modern medicines.

Key words: Bio-active, Efficacy, Mimela sp., Secondary metabolite, Therapeutic

 

 

 

Copyright © 2023 Triveni Enterprises. All rights reserved. No part of the Journal can be reproduced in any form without prior permission. Responsibility regarding the authenticity of the data, and the acceptability of the conclusions enforced or derived, rest completely with the author(s).