Journal of Environmental Biology

Antioxidant and antimicrobial properties of seed oil of Datura metel

R.K. Bachheti¹, I. Rai¹, V.K. Mishra²* and A. Joshi³

¹Department of Chemistry, Graphic Era University, Dehradun-248 002, India

²Department of Biotechnology, Doon P.G. Paramedical College, Dehradun-248 991, India

³Department of Environmental? Science, Graphic Era University, Dehradun-248 002, India

*Corresponding Author E-mail: mishravkbhu@gmail.com

 Key words

Antioxidant

Antimicrobial activity

Datura metel

Seed oil

Publication Data

Paper received : 23.05.2016????? Revised received : 29.11.2016??????????? Re-revised received : 16.03.2017

Accepted : 23.03.2017

Abstract

Aim: Dature metel is a valuable medicinal plant in traditional and contemporary systems of medicines in India, China and Africa. The present study aimed to evaluate antioxidant and antimicrobial properties of seed oil of Datura metel.

Methodology: The seeds of D. metel were extracted in Soxhlet apparatus with petroleum ether. The seed oil obtained was used for assessing the antioxidant capacity using radical scavenging (DPPH and nitric oxide) and reducing power. The antimicrobial potential of seed oil was assessed by agar diffusion and microdilution methods.

Results: The IC₅₀ of seed oil for nitric oxide radical scavenging was at par with standard antioxidant, curcumin (88 μg ml^-1 and 80 μg ml^-1) The reducing power ability of oil was higher than the reference ascorbic acid (IC₅₀ 8 and 22 ?g ml^-1). The study also showed significant antibacterial and anti-candidial activities of seed oil.    

Interpretation: Seed oil of Datura metel exhibited significant antioxidant and antimicrobial activities.

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