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Journal of Environmental Biology

pISSN: 0254-8704 ; eISSN: 2394-0379 ; CODEN: JEBIDP

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        Abstract - Issue Mar 2018, 39 (2)                                                                                                             Back

nstantaneous and historical temperature effects on a-pinene

Antioxidant and antimicrobial properties of seed oil of Datura metel


R.K. Bachheti1, I. Rai1, V.K. Mishra2* and A. Joshi3

1Department of Chemistry, Graphic Era University, Dehradun-248 002, India

2Department of Biotechnology, Doon P.G. Paramedical College, Dehradun-248 991, India

3Department of Environmental Science, Graphic Era University, Dehradun-248 002, India

*Corresponding Author E-mail:



 Key words


Antimicrobial activity

Datura metel

Seed oil




Publication Data

Paper received : 23.05.2016 Revised received : 29.11.2016 Re-revised received : 16.03.2017

Accepted : 23.03.2017



Aim: Dature metel is a valuable medicinal plant in traditional and contemporary systems of medicines in India, China and Africa. The present study aimed to evaluate antioxidant and antimicrobial properties of seed oil of Datura metel.


Methodology: The seeds of D. metel were extracted in Soxhlet apparatus with petroleum ether. The seed oil obtained was used for assessing the antioxidant capacity using radical scavenging (DPPH and nitric oxide) and reducing power. The antimicrobial potential of seed oil was assessed by agar diffusion and microdilution methods.


Results: The IC50 of seed oil for nitric oxide radical scavenging was at par with standard antioxidant, curcumin (88 μg ml-1 and 80 μg ml-1) The reducing power ability of oil was higher than the reference ascorbic acid (IC50 8 and 22 g ml-1). The study also showed significant antibacterial and anti-candidial activities of seed oil.    


Interpretation: Seed oil of Datura metel exhibited significant antioxidant and antimicrobial activities.




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