of ascorbic acid against oxidative stress-induced
toxicity in fish, Capoeta capoeta [Guldenstaedt, 1773]
Yilmaz1, İ.? Kaya2*, E. Ko?3, E. A.
Tanriverdİ1, M. M. Kaya2 and Y. Ersan4
Bioengineering, Faculty of Engineering and Architecture, Sinop University,
Biology, Faculty of Science and Letters, Kafkas University, 36100-Kars,
Bioengineering, Faculty of Engineering and Architecture, Kafkas University,
Histology and Embryology, Faculty of Medicine, Karabuk University,
Author E-mail: firstname.lastname@example.org
Paper received : 25.02.2016
Revised received : 18.05.2016
Re-revised received : 16.08.2016
Accepted : 09.11.2016
Aim: The main objective
of the present study was to evaluate the effect of ascorbic acid against
oxidative stress-induced by dimethoate in Capoeta capoeta.
fish caught in Kars Creek were randomized in four equal groups and acclimatized
in separate tanks. The fish were kept in tanks for 10 days as follows: Group
I (control) was kept in normal water, Group II, III and IV were kept in
separate tanks containing 2 mgl-1dimethoate and 2 mgl-1
dimethoate plus 100 mgl-1 ascorbic acid and ascorbic acid. The
level of total sialic acid, total antioxidant status and total oxidant status
in fish serum were analyzed.
sialic acid level of Group III was found to be lower than the level of Group
II (P< 0.05), there were no statistically important differences between
these two groups in total antioxidant status and oxidant status. In gills,
intensive cartilage degenerations and mononuclear cell infiltrations in group
II and III were observed. It was found that toxic effects of dimethoate in
group III decreased.
acid in fish exposed to dimethoate reduced the level of total sialic acid and
degenerations in lamellae of gills, it had no significant effect on the
oxidative stress response
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