JEB logo

Journal of Environmental Biology

pISSN: 0254-8704 ; eISSN: 2394-0379 ; CODEN: JEBIDP

About Journal
    Obituary: Dr. R. C. Dalela
    Editorial Board
    Reviewer Panel
    Publication Policies
    Guidelines for Editors
    Guidelines for Reviewers
    Abstracting and Indexing
    Subscription and Payments
    Contact Journal
    About Triveni Enterprises
Read Journal
    Current Issue
    Journal Archives
For Authors
    Guidelines for Authors
    Terms and Conditions
    Fees and Payments
    Track Paper Status

Google Search the Journal web-site:

    Abstract - Issue Jan 2014, 35 (1)                                     Back

nstantaneous and historical temperature effects on a-pinene

Effect of paracetamol and diclofenac on population growth

of Plationus patulus and Moina macrocopa 


S.S.S. Sarma1*, Brenda Karen Gonz?lez-P?rez2, Rosa Martha Moreno-Guti?rrez2 and S. Nandini1

1Universidad Nacional Aut?noma de M?xico, Campus Iztacala. Av. De los Barrios #1, Col. Los Reyes Iztacala,

Tlanepantla. Estado de M?xico. C.P. 54090, Mexico

2Posgrado en Ciencias del Mar y Limnolog?a, Universidad Nacional Aut?noma de M?xico, Mexico City, 04510, Mexico

*Corresponding Author E-mail:





 Publication Data

Paper received:

14 April 2013


Revised received:

15 June 2013



05 September 2013




Two non-steroidal anti-inflammatory commonly used in Mexico are paracetamol and diclofenac. These drugs reach natural waterbodies transport through the hydrological areas of agriculture and effluent treatment plants and can affect plankton. In this study, we quantified the chronic effects of paracetamol and sodium diclofenac on the population dynamics of the rotifer Plationus patulus and the cladoceran Moina macrocopa under laboratory conditions. Both these species of zooplankton are common in freshwaters and are sensitive to chemicals in the medium. Our results showed that densities of both P. patulus and M. macrocopa decreased with increasing levels of both the analgesic drugs. Both zooplankton species did not survive beyond when paracetamol was applied at 32 mg l-1 in the medium. Diclofenac in general had more adverse effect than paracetamol for either zooplankton species. P. patulus was more sensitive than M. macrocopa to both analgesic drugs. When diclofenac was present in the medium at ≥12.5 mg l-1, rotifer reproduction was inhibited, while the tested cladocerans continued to grow but to lower densities compared to control. The rate of population increase (r) per day of P. patulus and M. macrocopa was significantly and inversely related to the concentration of paracetamol and diclofenac in the medium. However, the relationship between r and drug concentration differed depending on the zooplankton species and drug. In controls, the r of P. patulus was 0.18 d-1, for M. macrocopa under similar conditions, it was slightly lower (0.16 d-1). The r values of both zooplankton populations became negative (-0.10 to -0.15 d-1) when exposed to paracetamol at 32 mg l-1 or diclofenac at 25 mg l-1.

Key words




Cladocera, Pain relievers, Rotifera, Sublethal effects



Copyright ? 2014 Triveni Enterprises. All rights reserved. No part of the Journal can be reproduced in any form without prior permission. Responsibility regarding the authenticity of the data, and the acceptability of the conclusions enforced or derived, rest completely with the author(s).