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Beta-lactamases
production and antimicrobial resistance ratio of Pseudomonas aeruginosa
from hospitalized
patients
in Kahramanmaras, Turkey
Sevil
Toroglu1*, Hatice Avan1?and Dilek Keskin2
1*Department of Biology,
Faculty of Arts and Science, Kahramanmaras S?t?? Imam University,
Kahramanmaras- 461 00, Turkey
2??ine High Vocational School,
Adnan Menderes University, ?ine-Aydin- 095 00, Turkey
*Corresponding
Author email : storoglu@ksu.edu.tr
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Publication
Data
?Paper received:
?12 November 2010
?Revised received:
?12 January 2012
?Accepted:
?17 March 2012
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Abstract
Sixteen
isolates of P. aeruginosa were collected from different hospitals in
Kahramanmaras among 2006-2007 and tested for the level of resistance to the
widely used antipseudomonal antibiotics and used in local midicinal and veterinary
practice. The aim of this study was to determine the antibiotic resistance to
P. aeruginosa strains isolated in Microbiology Laboratory of different
hospitals in Kahramanmaras between 2006-2007. These strains were mostly
isolated from urine and few from tracheolaringeal aspirate, tracheal
secretion, mucus, bronchoalveolar lavage. The antibiotic resistance rates
were as follows: Penicillin (PEN) 100%, Amoxicillin (AMO) 94%, Cefazolin (CEF)
87.5%, Cefoxitin (CEFX) 81%, Nitrofrantoin (NIT) 75%, Chlorampenicol (CHL)
62.5 %, Tetracycline (TET) 56%, Ceftriaxone (CEFT) 44%, Oflaxain (OFL) and
Gentamycin (GEN) 37.5%, Meropenem (MER) and Streptomycine (STR) 31%. Among 16
isolates of P.aeruginosa from wounds showed 8 (50%) b-lactamase
activity, whereas 8 isolates of P.aeruginosa from urine? showed no b-lactamase
activity. All P. aeruginosa strains 16 (100%) isolates showed multiple
antibiotic resistance towards three to eleven antibiotics.
Key words
P.
aeruginosa, Antibiotic resistance, Beta-lactamase activity
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Copyright
? 2013 Triveni Enterprises. All rights reserved. No part of the Journal can
be reproduced in any form without prior permission. Responsibility regarding
the authenticity of the data, and the acceptability of the conclusions
enforced or derived, rest completely with the author(s).
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