Journal of Environmental Biology
pISSN: 0254-8704 ; eISSN: 2394-0379 ; CODEN: JEBIDP
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Abstract - Issue Jul 2008, 29 (4) Back
Segregation distortion at a
microsatellite marker in the olive
Jung Ha Kang*1, Jong Hyun Kim2, Hyun Chul Kim2, Jae Koo Noh2, Jeong Ho Lee2 and Kyung Kil Kim2
Institute, National Fisheries Research and Development Institute, 619-902,
Republic of Korea
(Received: June 29, 2007; Revised received: February 18, 2008; Accepted: February 25, 2008)
Abstract: In the course of quantitative trait loci (QTL) analysis of the back cross (BC1) families of olive flounder (Paralichtys olivaceus), we observed significant segregation distortion at a microsatellite marker, Poli9-58TUF in two crosses of informative progenies. The family 1 of the random BC1 progenies derived from a cross between a F1 male genotype (A/B) and? a F1?s female parent genotype (A/C) and the family 2 (A/C x A/C) displayed a strong bias in the locus from the Mendelian inheritance by the elimination of homozygous A/A genotype. The deleterious roles of the AA genotypes are suggested during the metamorphosis and it implies that the parents of these families carried a recessive gene or genes hampering development at an early stage because the offspring of the double heterozygote parents show the reduction in frequency or elimination of one homozygous class, which is an evidence for linkage between the genetic marker and gene(s) with recessive deleterious alleles. This data support a hypothesis that the region contains a recessive lethal gene or genes.
Key words: Segregation distortion, Microsatellites, Paralichtys olivaceus, Lethal gene
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