Journal of Environmental Biology
pISSN: 0254-8704 ; eISSN: 2394-0379 ; CODEN: JEBIDP
Search the Journal web-site through Google:
Abstract - Issue Jul 2008, 29 (4) Back
Antioxidant activity of mojabanchromanol, a novel chromene,
Sun Hee Cho1, Ji Young Cho2, Se Eun Kang1, Yong Ki Hong1 and Dong Hyun Ahn*1
1Faculty of Food Science and
Biotechnology, Pukyong National University, Busan, 608-737,
(Received: March 13, 2007; Revised received: December 18, 2007; Accepted: December 19, 2007)
Abstract: Silica gel chromatography, HPLC, EI -Mass, and NMR analyses were performed in order to determine the structure obtained from the separation and refinement of the main components of an ethanol extraction of Sargassum siliquastrum, which indicated its antioxidant activity. An ethanol extraction of Sargassum siliquastrum demonstrated the strongest antioxidant activities of ethyl acetate when isolated by silica gel chromatography. This amounts to 84.9±1.2% of its 0.5 mg ml-1 concentration. The thiobarbituric acid reactive substances (TBARS) measurements from 3 isolations of an HPLC separation of ethyl acetate showed that the antioxidant activity of peak 2 was the most dominant at 84.08% in a 0.5 mg ml-1 concentration. Peak 2 was verified as a type of chromene through EI-Mass and NMR analysis. Its metal sealing characteristic was low while its characteristic of TBARS and DPPH erasure indicated similar or higher levels of metal sealing characteristic. The NMR spectroscopic data was used to elucidate the structure of this new compound, which showed strong antioxidant activity in the assay.
Key words: Antioxidant activity, Chromene, Brown alga, Sargassum siliquastrum
PDF of full length paper is available with author (email@example.com)
Copyright © 2008 Triveni Enterprises. All rights reserved. No part of the Journal can be reproduced in any form without prior permission. Responsibility regarding the authenticity of the data, and the acceptability of the conclusions enforced or derived, rest completely with the author(s).