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Journal of Environmental Biology

pISSN: 0254-8704 ; eISSN: 2394-0379 ; CODEN: JEBIDP

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    Abstract - Issue Mar 2009, 29 (2)                                     Back


Ovarian development in Labeo dyocheilus (McClelland) during active

Influence of endosulfan and monocrotophos exposure on the activity of NADPH cytochrome C reductase (NCCR) of Labeo rohita (Ham)

K. Ramaneswari and L.M. Rao*

Department of Zoology, Andhra University, Visakhapatnam-530 003, India

(Received: March 06, 2005 ; Revised received: July 10, 2006 ; Accepted: August 12, 2006)

Abstract: The response of NADPH cytochrome C reductase (NCCR) activity in liver of Labeo rohita fish exposed to the pesticides, 0.25 mgl -1endosulfan and 2 mg/l monocrotophos was studied. In terms of specific enzyme activity (mU/mg protein) a significant level of NCCR was observed in the liver tissues of Labeo rohita exposed to the pesticides, when compared to the control fish (2.460  mU/mg protein). Increase of NCCR activity was more in the liver of the fish exposed to monocrotophos(4.595 mU/mg protein) than those exposed to endosulfan (2.850 mU/mg protein).  The results demonstrate that the pesticides, endosulfan and monocrotophos, interfere with NADPH dependent monoxygenase mechanism and are effective inducers of NADPH cytochrome C reductase. The activity of NCCR in the liver tissue of Labeo rohita may serve as a useful tool for monitoring aquatic pollution.

Key words:     Labeo rohita, Pesticides, Endosulfan, Monocrotophos, Liver tissue, NADPH cytochrome C reductase, Biomarker

PDF of full length paper is available with author (lmrao4547@yahoo.com)

 

 

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