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Journal of Environmental BiologypISSN: 0254-8704 ; eISSN: 2394-0379 ; CODEN: JEBIDP |
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Abstract - Issue Mar 2009, 29 (2) BackInfluence of endosulfan
and monocrotophos exposure on the activity of NADPH cytochrome C reductase (NCCR) of Labeo rohita (Ham)
K. Ramaneswari
and L.M. Rao* Department of Zoology, (Received: March 06, 2005
; Revised received: July 10, 2006 ; Accepted: August 12, 2006) Abstract: The response
of NADPH cytochrome C reductase
(NCCR) activity in liver of Labeo rohita
fish exposed to the pesticides, 0.25 mgl
-1endosulfan and 2 mg/l monocrotophos
was studied. In terms of specific enzyme activity (mU/mg
protein) a significant level of NCCR was observed in the liver tissues of Labeo rohita exposed to the
pesticides, when compared to the control fish (2.460 mU/mg
protein). Increase of NCCR activity was more in the liver of the fish exposed to monocrotophos(4.595 mU/mg protein) than those exposed to endosulfan
(2.850 mU/mg protein). The results demonstrate that the pesticides, endosulfan and monocrotophos,
interfere with NADPH dependent monoxygenase mechanism
and are effective inducers of NADPH cytochrome C reductase. The activity of NCCR in the liver tissue of Labeo rohita may serve as a
useful tool for monitoring aquatic pollution. Key words: Labeo rohita, Pesticides, Endosulfan, Monocrotophos, Liver tissue, NADPH cytochrome
C reductase, Biomarker PDF of full length paper is available with author (lmrao4547@yahoo.com) Copyright
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