Journal of Environmental Biology

Total ATPases activity in different tissues of albino mice exposed to aluminium acetate

N. John Sushma² and K. Jayantha Rao*¹

¹Department of Zoology, Sri Venkateswara University, Tirupati-517 502, India

²Department of Biotechnology, Sri Padmavathi Mahila University, Tirupati-517 502, India

(Received: April 05, 2005 ; Revised received: December 12, 2005 ; Re-revised received: May 04, 2006 ; Accepted: June 13, 2006)

Abstract: This study has revealed significant variation in total ATPase activity after administration of aluminium acetate in different tissues of albino mice. With sublethal dose (3.5 mg/kg body weight) of aluminium acetate, total ATPase activity was decreased in brain (-50.61), liver (-50.69), kidney (-30.74), heart (-64.07), muscle (-51.50) and testis (-65.53) of albino mice. The decrement was enhanced with the increase of aluminium acetate. ATPases play an important role in the maintenance of cell permeability and energy transformation in the biological system. The results suggest that ATPase has a particular sensitivity to aluminium acetate.

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