Journal of Environmental Biology

Histopathological changes in liver of Heteropneustes fossilis exposed to cypermethrin

Namita Joshi*¹, Dharmlata¹ and A.P. Sahu²

¹Department of Environmental Science, Kanya Gurukul Mahavidyalaya, Jwalapur, Hardwar - 249 407, India

²Department of Preventive Toxicology, I.T.R.C., Lucknow - 226 001, India

(Received: January 25, 2005 ; Revised received: October 01, 2005; Accepted: October 29, 2005)

Abstract: Cypermethrin was administered to Heteropneustes fossilis in chronic concentration to determine lesion of liver as indicators of tissue damage. The cypermethrin dose used was ¼ of 96 hr LC₅₀. Histopathological changes in liver ranged from vacuolization, necrosis, fibrosis of perivascular region and disposition of yellow brown grains at different time of exposure viz; 20^th, 30^th, 40^th and 60^th days

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